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Image Number #1586 (Papulonecrotic tuberculids)

Diagnosis: Papulonecrotic tuberculids

Description: Close up of necrotizing papules

Morphology: Papules

Site: Knee

Sex: M

Age: 45

Type: Clinical

Submitted By: Shahbaz Janjua

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Differential Diagnosis
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History: Papulonecrotic tuberculids (PNT) were first described by Darier in 1896.  Tuberculids represent a cutaneous hypersensitivity reaction or an exaggerated host immunologic response to TB antigens released from a distant focus of infection. Most patients react markedly to the Mantoux skin test.  PNT is a chronic, recurrent, and symmetric eruption of necrotizing skin papules arising in crops, involving primarily extensor surfaces, particularly the knees, the elbows, and the dorsa of the hands and the feet.  The lesions heal with varioliform scarring. 

DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Papulonecrotic tuberculids"

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