Diagnosis: Pemphigoid bullous
Description: grouped blisters
Morphology: Blisters
Site: Thigh
Sex: F
Age: 70
Type: Clinical
Submitted By: Ian McColl
Differential DiagnosisHistory: This elderly lady initially had an itchy urticarial rash on her trunk and limbs but after a few weeks she suddenly developed these tense grouped blisters.Immunofluorescence showed IgG and C3 deposited on the basement membrane.She responded rapidly to oral steroids and subsequently Imuran as a steroid sparer was used along with topical steroids to any small areas of skin where the urticarial rash was recurring.