Diagnosis: Pemphigoid bullous
Description: Grouped confluent peripheral blisters
Morphology: Blisters
Site: Thigh
Sex: M
Age: 72
Type: Clinical
Submitted By: Ian McColl
Differential DiagnosisHistory: Bullous pemphigoid is an immunobullous disease characterised by splitting of the epidermis at the dermoepidermal junction with IgG and C3 deposited at the basement membrane.The blisters are firm,sometimes blood stained and often found in the groins or axillae.They heal without scarring.There may be a preceding phase with urticarial erythema before the blisters actually form.This is the commonest immunobullous disease in the elderly.