Diagnosis: Pseudoxanthoma elasticum
Description: Note the broken curled elastic fibres in the dermis with some deep calcification.
Morphology: Papules,yellow
Site: Groin adult
Sex: M
Age: 35
Type: Clinical & Histology
Submitted By: Ian McColl
Differential DiagnosisHistory:
Pseudoxanthoma elasticum is a rare inherited disease with damage to elastic fibres in the skin causing weakness of the skin with loss of elaticity.As the elastic fibres in blood vessels are also involved patients are susceptible to strokes and heart attacks at an early age.
The patient shown above had already had a stroke at aged 35.His groin skin was very lax due to the loss of elasticity.His images show the classic plucked chicken appearance.This is described as the finding of multiple yellowish flat topped papules both discrete and confluent , in the skin creases of the sides of the neck and the flexures.